Maarten Altelaar
develops and implements novel MS based proteomics technologies to study protein regulation and cellular signaling processes. Emphasis lies on neuronal cell differentiation and cancer signaling in acquired drug resistance and immune therapy. High-throughput (phospho)proteomics complemented with top-down MS technologies are used to target proteome dynamics

Positions and Projects

 

We offer interesting research internships for students.

We are always looking for talented candidates. Are you an excellent researcher in the field of Proteomics, bioinformatics or computational biology and you like to combine this with interesting biological questions? Please send me an email with your CV and a letter of motivation.

 

Currently looking for a postdoc with experience in clinical plasma proteomics

 

In this project we aim to identify soluble factors present in melanoma patients’ plasma, that are responsible for systemic immune suppression, which hampers T cell activation upon checkpoint inhibitor treatment. In a collaborative effort with the NKI we will analyze systemic treatment naïve plasma samples by deep proteomic profiling from stage III melanoma patients that have progressed to stage IV. Changes in the profile of the identified proteins will be tested in an independent cohort of 100 melanoma patients treated with ipilimumab+nivolumab from whom we have collected baseline serum samples.

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